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Cajun chicken and sausage alfredo with creamy pasta in a skillet.

Cajun chicken and sausage alfredo​


  • Author: Emma Hart
  • Total Time: 35 minutes
  • Yield: 4 servings 1x

Description

Cajun Chicken and Sausage Alfredo is a bold, creamy, and hearty one-pan dish that brings Southern flavors to your dinner table. Juicy, Cajun-seasoned chicken and smoky andouille sausage are tossed in a rich Alfredo sauce made with heavy cream and fresh Parmesan, then combined with tender pasta for the ultimate comfort food. It’s easy to make, perfect for weeknight meals or entertaining, and customizable with vegetables or dairy-free alternatives.


Ingredients

Scale

Core Ingredients

2 boneless, skinless chicken breasts
8 oz andouille sausage, sliced
2 tablespoons Cajun seasoning
2 tablespoons olive oil
3 cloves garlic, minced
1 ½ cups heavy cream
1 cup freshly grated Parmesan cheese
8 oz fettuccine or penne pasta
Salt, to taste
Black pepper, to taste

Optional Additions

1 bell pepper, sliced
1 cup baby spinach
½ cup mushrooms, sliced
¼ teaspoon red pepper flakes
2 oz cream cheese or shredded mozzarella
Chopped fresh parsley or scallions, for garnish


Instructions

  • Season and Cook the Chicken
    Generously season the chicken breasts with Cajun seasoning. Heat olive oil in a large skillet over medium-high heat. Sear the chicken for 4–5 minutes per side, until golden and cooked through. Remove and let rest before slicing.

  • Sear the Sausage
    In the same skillet, add sliced andouille sausage. Cook until browned and crisp around the edges to enhance the smoky flavor. Remove and set aside.

  • Build the Alfredo Sauce
    Reduce heat to medium-low. Add minced garlic to the sausage drippings and sauté for 30 seconds. Pour in heavy cream and bring to a gentle simmer. Stir in Parmesan cheese and continue stirring until the sauce is smooth and creamy.

  • Cook the Pasta
    Meanwhile, boil pasta in salted water until al dente. Drain, reserving ¼ cup of pasta water.

  • Combine Everything
    Add sliced chicken and sausage back into the sauce. Stir in the drained pasta and toss to coat. Use reserved pasta water as needed to loosen the sauce. Garnish with parsley or scallions and serve hot.

Notes

  • Use freshly grated Parmesan for the smoothest texture pre-shredded cheese can result in a grainy sauce.

  • To cut spice, stir in extra cream or cheese; to boost heat, sprinkle red pepper flakes.

  • This dish reheats well just add a splash of cream or milk when warming.

  • You can make it dairy-free by using coconut cream and vegan Parmesan.

  • For a twist, substitute chicken with shrimp or tofu for alternate proteins.

  • Prep Time: 10 minutes
  • Cook Time: 25 minutes
  • Category: Dinner
  • Method: Stovetop
  • Cuisine: Cajun, American

Nutrition

  • Serving Size: 1.5 cups
  • Calories: 680
  • Sugar: 3g
  • Sodium: 990mg
  • Fat: 38g
  • Saturated Fat: 18g
  • Unsaturated Fat: 17g
  • Carbohydrates: 48g
  • Fiber: 2g
  • Protein: 38g
  • Cholesterol: 155mg

Keywords: cajun chicken alfredo, chicken and sausage pasta, creamy cajun pasta, easy cajun alfredo, one-pan pasta, andouille sausage pasta